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PBSerum Medical Video

Introduction and information (in English and Polish):

PBSerum Medical Video

General update and focus on protocols review:

PBSerum HA Correctors

HA TOTAL corrector & HA PARTIAL corrector

Viktige forsiktighetsregler ved bruk av PBSerum på voksen hud 49+

from expert trainer I. Paretes – Proteos Biotech, Madrid


I have been looking into a possible cause regarding the adverse event you have observed in some patients after anti-flaccidity treatment with HIGH. After reading several scientific reviews, and taking into accout that these patients are mostly elderly patients and they had no previous filler, I think that this problem is related to the aging-derived anatomical changes. From my point of view, this could be the explanation:


With aging we observe ptosis of soft tissues, such as fat pads migrations in the face, particularly in the lower cheek. As you can see in the picture below, it is very important to distinguish between malar fat (in red) and jowl fat (in green). With aging, malar fat decreases and goes down, creating hollowing of the temple, the lateral cheek and the central cheek. In elderly patients, both fat pads become closer between each other, which makes more difficult to apply the enzymes where they should be applied. In these elderly patients we need to be extra careful, because it is crucial to specifically delimit just the lower third in order to reduce jowl fat without reducing malar fat, which is not our target. If the lipase degraded malar fat, we would be enhancing the hollowing even more, causing a facial depression, so malar fat shouldn’t be touched.


Therefore, when you carry out anti-flaccidity therapy in these patients, the enzymes should be placed intradermally through a very superficial infiltration, in order to avoid destroying malar fat. The only specific location where you could perform retroinjection (retrograde) would be jowl fat, in order to let the lipase degrade it, but the number of retroinjections should be very limited. The older the patient is, the more superficial you apply the enzymes, this is my recommendation.


Sertifiserte kursdeltagere

Med expert trainer for Skandinavia, Sandra Romano

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